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DSECT/DSEN Monthly Seminar Series - May 27 2021 - Available medications used as potential therapeutics for COVID-19 in pregnancy

“Available medicatioms used as potential therapeutics for COVID-19: What are the known safety profiles in pregnancy”

 

Presented by

Dr. Anick Bérard PhD FISPE

Full Professor, Faculty of Pharmacy, University of Montreal and CHU Ste-Justine

Thursday, May 27, 2021 3- 4pm EST

 

Abstract: 

Medications already available to treat other conditions are presently being studied in clinical trials as potential treatments for COVID-19. Given that pregnant women are excluded from these trials, we aimed to investigate their safety when used during pregnancy within a unique population source. Using the population-based Quebec Pregnancy Cohort, we identified women who delivered a singleton liveborn (1998-2015). Taking potential confounders into account including indications for use, the risk of prematurity, low birth weight (LBW), small for gestational age (SGA), and major congenital malformation (MCM) associated with COVID-19 repurposed drug use during pregnancy were quantified using generalized estimation equations.

Learning Objectives: 

  1. Repurposed medications have great potential for identifying COVID-19 therapeutics in a fast-track manner
  2. Pregnant women are excluded from most of these clinical trials, hence the need to study safety on large population-based observational cohorts.
  3. Risk profiles of repurposed medications during pregnancy need to be assessed

Supporting Resources:

  • to come