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DSECT/DSEN Monthly Seminar Series - May 24, 2018


“Random effects versus fixed effect meta-analysis in a distributed network setting”


Presented by

Colin Dormuth, CsD

Associate Professor, Faculty of Medicine, University of British Columbia


Thursday, May 24, 2018 3-4pm EDT

Online via GoToWebinar





Random effects (RE) versus fixed effect (FE) meta-analysis is discussed in the context of a distributed drug safety network. The webinar begins with a brief introduction into the theory of RE and FE meta-analysis, which is then followed by a learning example on a hypothetical drug analyzed in the CNODES network. Some additional theory is then presented before proceeding with a second applied exercise.

Learning Objectives:

1. To impart a basic understanding of important quantitative and qualitative aspects of random effects versus fixed effect meta-analysis.

2. Through quantitative data exploration in MS Excel, attendees will learn the quantitative intuition behind fixed effect versus random effects meta-analysis.