Imir George Metushi
Imir finished his BSc with honors in Chemistry from York University specializing in the Analytical Chemistry stream. He is now working towards his PhD in Pharmacology at the University of Toronto under the supervision of Dr Jack Uetrecht. Imir’s main interest is to understand the mechanism of idiosyncratic drug reactions. Specifically he is interested in developing animal models of idiosyncratic drug-induced liver injury. He is also doing clinical studies to make sure that the animal models reflect the mechanisms of idiosyncratic reactions in humans. These studies bridge several disciples and techniques including drug metabolism, immunotoxicology, molecular biology, and histopathological techniques. It is through such multidisciplinary studies that we will be able to predict and prevent idiosyncratic drug reactions, which represent a significant clinical problem and also significantly add to the uncertainty of drug development.